Midi Weight Loss is a medical weight management program offered by Midi Health, a telehealth company focused on women in midlife. It combines prescription weight loss medications, lifestyle counseling, and hormone health assessments to help women lose weight. The program is designed specifically for women going through perimenopause and menopause, when weight gain often becomes harder to control.
What Is Midi Weight Loss?
Midi Weight Loss is not a diet or a supplement. It is a clinical program that treats obesity and weight gain as medical conditions. A licensed provider — usually a nurse practitioner or doctor — evaluates your health, hormone levels, and weight history. Then they create a treatment plan that may include FDA-approved weight loss medications, nutrition coaching, and support for sleep, stress, and movement.
The program is delivered entirely through telehealth. This means you have video visits with the provider and message them between appointments. Midi Health accepts many insurance plans for the visits, though medication costs can be separate.
What makes Midi different from a standard weight loss clinic is its focus on women in midlife. The providers are trained to recognize how changes in estrogen and progesterone affect metabolism, appetite, and fat storage. They look for underlying issues like thyroid problems or insulin resistance that can make weight loss harder.
How Does the Midi Weight Loss Program Work?
You start with a thorough medical history and a discussion of your symptoms. The provider may order blood tests to check hormone levels, thyroid function, fasting glucose, and lipid panel. This information helps them understand why you may be gaining weight or struggling to lose it.
Based on your results, the provider prescribes medication if you meet the medical criteria. The most common medications used are GLP-1 agonists like semaglutide (Wegovy) and tirzepatide (Zepbound). These drugs are approved for chronic weight management and work by slowing stomach emptying and reducing appetite. Some women may also be prescribed metformin if they have insulin resistance or a lower BMI.
The program includes ongoing coaching. A health coach helps you set realistic goals around food choices, physical activity, sleep habits, and stress management. This part is not a rigid meal plan — it is tailored to your lifestyle. You check in with the provider every few weeks to adjust medication dose and address side effects.
The typical program lasts at least several months. Most people continue medication for a year or longer if they are losing weight and tolerating it well.
Who Is a Good Candidate for Midi Weight Loss?
The program is designed for women in perimenopause or menopause who have a BMI of 30 or higher, or a BMI of 27 or higher with a weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol. These are the same criteria used by most medical weight loss programs.
You should also be willing to commit to lifestyle changes. Medication alone works better when combined with healthy eating and regular activity. The program is not a quick fix. It requires regular appointments, lab work, and honest communication about how you are doing.
People who are pregnant, breastfeeding, or have a personal or family history of medullary thyroid cancer or certain pancreatic conditions should not take GLP-1 medications. The provider will screen for these contraindications during the initial visit.
What Does the Evidence Say About Midi Weight Loss?
There are no published studies specifically on the Midi Weight Loss program. However, the medications they prescribe have strong evidence from large clinical trials. Research consistently shows that GLP-1 agonists such as semaglutide lead to significant weight loss. In major trials, people taking these medications lost an average of 10 to 15 percent of their starting body weight over about a year. Tirzepatide has shown even greater average weight loss in some studies.
The lifestyle coaching component is based on standard behavioral weight loss strategies that have been studied for decades. Combining medication with structured support generally produces better results than medication alone. However, the quality of coaching can vary between providers, and Midi’s specific coaching approach has not been separately evaluated.
Some critics point out that telehealth weight loss programs may not be as effective as in-person medical supervision for people with complex health issues. For otherwise healthy individuals, telehealth appears to be a reasonable alternative. More research is needed comparing telehealth programs head-to-head.
What Are the Risks and Side Effects?
The most common side effects of GLP-1 medications are nausea, vomiting, diarrhea, constipation, and abdominal pain. These usually improve over time, especially if the dose is increased slowly. Some people cannot tolerate the side effects and stop treatment.
More serious but rare risks include pancreatitis, gallbladder disease, kidney injury, and severe allergic reactions. There is also a possible increased risk of thyroid C-cell tumors, which is why the medication is not recommended for people with a family history of medullary thyroid cancer.
Hormone therapy, if prescribed as part of the program, carries its own risks including blood clots and breast cancer. The provider should review your personal and family history carefully before prescribing hormones.
Weight regain is also a real risk. Many people gain back some or all of the weight once they stop taking the medication. Long-term weight maintenance requires continued healthy habits and possibly ongoing or intermittent medication use.
How Much Does Midi Weight Loss Cost?
The cost varies depending on your insurance and the specific medications prescribed. The initial visit and follow-up appointments are often covered by insurance if you have a qualifying condition like obesity. Midi Health publishes a list of accepted insurance plans on their website.
The medications themselves can be expensive. With insurance coverage, a month’s supply of Wegovy or Zepbound may cost between $25 and $50 for many plans. Without insurance, the list price is several hundred dollars per month. Some people access lower-cost options through manufacturer savings cards or by using compounded semaglutide, though compounded versions are not FDA-approved and carry quality risks.
The lifestyle coaching and support is included in the visit fee. There are no separate membership or program fees beyond the medical visits and medication.
Frequently Asked Questions
Is Midi Weight Loss covered by insurance?
Midi Health accepts many major insurance plans for the medical visits. Medication coverage depends on your specific plan and whether you meet the plan’s requirements for weight loss drugs.
How quickly can I expect results with Midi Weight Loss?
Most people see some weight loss in the first month, but meaningful changes take several weeks. Typical weight loss is 1 to 2 pounds per week after the medication dose is stable.
Do I need to be menopausal to join Midi Weight Loss?
No. The program is designed for women in midlife, including perimenopause and postmenopause. Women younger than 40 with hormone-related weight issues may also be considered.
Can I use Midi Weight Loss if I am already on another weight loss program?
You should discuss any current programs with the Midi provider. Combining medical treatment with other intensive programs could lead to unsustainable calorie restriction or unsafe medication interactions.
