Mi Paste Plus is a dental cream that helps strengthen tooth enamel and reduce tooth sensitivity. It contains casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride. You apply it directly to your teeth, usually after brushing, to remineralize early decay and protect against cavities.
What Is Mi Paste Plus?
Mi Paste Plus is a topical dental product made by GC Corporation. It combines two active ingredients: CPP-ACP (a milk-derived protein compound) and 900 ppm fluoride. The CPP-ACP binds calcium and phosphate ions to the tooth surface, making them available to rebuild enamel. The fluoride adds another layer of protection by forming fluorapatite, which is more resistant to acid attacks.
This product is different from regular toothpaste. It is not meant for daily brushing. Instead it is used as a treatment cream, often in custom dental trays or applied directly to sensitive or weakened areas. Dentists commonly recommend it for patients with high cavity risk, enamel erosion, or tooth sensitivity.
What Are the Uses of Mi Paste Plus?
Mi Paste Plus has three main uses supported by clinical research.
Remineralizing early enamel lesions. White spots on teeth are early signs of decay. CPP-ACP helps push calcium and phosphate back into the enamel before a cavity forms. Fluoride boosts this process. Studies show that combining these ingredients can reverse early non-cavitated lesions.
Reducing tooth sensitivity. Exposed dentin causes sharp pain from hot, cold, or sweet stimuli. The calcium and phosphate in Mi Paste Plus block open tubules in the dentin. This reduces fluid movement inside the tooth and lowers nerve irritation. Many patients notice relief within a few weeks of consistent use.
Protecting against acid erosion. Acid from foods, drinks, or stomach reflux softens enamel. Applying Mi Paste Plus after an acid exposure can help re-harden the surface. It does not prevent the acid damage itself, but it aids recovery afterward.
What Are the Benefits of Mi Paste Plus?
The main benefit is that it provides more calcium and phosphate than saliva alone can supply. During early decay, the tooth loses minerals faster than it can regain them. Mi Paste Plus delivers a concentrated source directly to the enamel surface.
Several other benefits matter to patients. It is sugar-free and does not cause cavities. It contains no harsh abrasives, so it is safe for daily use on sensitive teeth. The flavor is mild (often mint or strawberry) and it leaves a clean feeling. Because it is a topical cream you apply only where needed, you avoid systemic exposure to fluoride beyond what you normally get from toothpaste.
Research published in dental journals has found that CPP-ACP combined with fluoride is more effective at remineralizing subsurface lesions than fluoride alone. This does not mean it replaces fluoride toothpaste and professional care. It adds an extra layer of protection for those who need it.
How Do You Apply Mi Paste Plus Correctly?
Proper application maximizes the results. Follow these general steps, but always check the instructions from your dentist or the product label. Individual cases may differ.
Step 1: Brush and floss your teeth normally. Rinse thoroughly to remove plaque and debris.
Step 2: Dry the tooth surfaces slightly with a clean tissue or cotton roll. A dry surface helps the cream adhere.
Step 3: Squeeze a small amount of Mi Paste Plus onto your fingertip or directly onto the teeth. A pea-size amount is enough for all teeth, or a smaller amount for a single sensitive area.
Step 4: Spread the cream over the teeth or the specific spots. If you are using a custom tray, fill the tray with a thin layer and place it over your teeth. The manufacturer recommends leaving the cream on for at least three minutes—up to five minutes is common. Some dentists advise leaving it on overnight when using trays for sensitivity.
Step 5: After the time is up, spit out any excess. Do not rinse with water. Rinsing washes away the active ingredients and reduces the benefit. If the feeling of the cream bothers you, you may rinse, but try to resist for at least 30 minutes.
For best results, use Mi Paste Plus after your evening brushing so the cream remains undisturbed for a longer period. Do not eat or drink for at least 30 minutes after application.
Is Mi Paste Plus Safe?
Mi Paste Plus is generally safe when used as directed. The main safety concern is the fluoride content. Each application delivers a small amount of fluoride. Because it is not swallowed, the risk is low. However, if you or a child accidentally swallows a large amount, call poison control. Do not use in children younger than six unless a dentist specifically recommends it and supervises use.
People with milk protein allergy should avoid Mi Paste Plus. The CPP-ACP is derived from casein, a milk protein. It can cause allergic reactions in individuals with confirmed casein allergy. For others, no significant side effects have been reported from standard use. Some users notice a temporary chalky texture, but this is not harmful.
Pregnant or breastfeeding women should consult their dentist before use. No studies have evaluated safety in pregnancy, but because the product is topical and used in small amounts, it is generally considered low risk. No clinical guidelines currently exist for this population, so professional advice is best.
Mi Paste Plus vs. Mi Paste: What’s the Difference?
The most important difference is fluoride. Regular Mi Paste contains CPP-ACP but no added fluoride. Mi Paste Plus has 900 ppm fluoride. If you already use a fluoride toothpaste and drink fluoridated water, the extra fluoride in Plus may not be necessary for everyone. Your dentist can help decide which formulation fits your risk profile.
Mi Paste is often recommended for patients who are sensitive to fluoride or who want to avoid it, such as very young children. Mi Paste Plus is preferred for adults with active decay risk or significant sensitivity. Both products rely on the same CPP-ACP technology for remineralization, but the Plus version adds the proven cavity-fighting benefit of fluoride.
Frequently Asked Questions
Can I use Mi Paste Plus every day?
Yes, daily use is safe and recommended for most people, especially if you have high cavity risk or ongoing sensitivity. Use it once a day after brushing, typically before bed.
How long does it take to see results from Mi Paste Plus?
Many users notice reduced sensitivity within a few weeks. Remineralization of white spots takes longer, often two to six months of consistent use. Results vary by individual.
Do I need a prescription for Mi Paste Plus?
In many countries Mi Paste Plus is available without a prescription. However, dentists often recommend it as part of a treatment plan. Buying from a dental office ensures you get the correct product and usage advice.
Can I swallow Mi Paste Plus?
No, it is not meant to be swallowed. If you accidentally swallow a small amount, it is unlikely to cause harm. For larger amounts, contact a healthcare provider or poison control.
