Healthcare professionals clean their hands at specific moments to prevent the spread of infections. The World Health Organization (WHO) defines five key moments: before touching a patient, before clean or aseptic procedures, after body fluid exposure risk, after touching a patient, and after touching patient surroundings. These moments are not just suggestions — they are the standard of care in hospitals, clinics, and other healthcare settings worldwide.
What Are the Five Moments for Hand Hygiene?
The WHO’s “Five Moments for Hand Hygiene” framework is the global standard. It was developed to make hand hygiene decisions simple and consistent for healthcare workers.
The five moments are:
- Before touching a patient — This protects the patient from germs carried on your hands.
- Before clean or aseptic procedures — This prevents germs from entering the patient’s body during tasks like wound care, inserting IV lines, or giving injections.
- After body fluid exposure risk — This protects you from blood, saliva, urine, or other body fluids you may have contacted.
- After touching a patient — This protects you and the next patient from germs you picked up during patient contact.
- After touching patient surroundings — This covers surfaces like bed rails, bedside tables, and medical equipment that may carry germs.
These moments apply to every healthcare worker who has direct patient contact. That includes doctors, nurses, therapists, technicians, and support staff.
Why Do These Specific Moments Matter?
Each moment targets a specific route of germ transmission. Understanding the reasoning makes the practice easier to follow consistently.
Before touching a patient, your hands may look clean but still carry invisible germs from previous tasks. The “before aseptic procedures” moment is especially critical. Aseptic procedures involve sterile body sites or medical devices. Introducing even a small number of germs can cause serious infections like bloodstream infections or surgical site infections.
The “after body fluid exposure” moment protects healthcare workers themselves. Bloodborne pathogens like hepatitis B, hepatitis C, and HIV can be transmitted through contact with infected blood. Soap and water or an alcohol-based hand rub immediately after exposure reduces this risk significantly.
After touching a patient or their surroundings, your hands become a vehicle. Without cleaning, you transfer those germs to the next surface or person you touch. This is how many hospital-acquired infections spread.
When Should You Use Soap and Water Versus Hand Sanitizer?
Alcohol-based hand sanitizer is the preferred method for routine hand hygiene in healthcare settings. It is fast, effective, and less drying to skin than soap and water. However, there are specific situations where soap and water are required.
Use soap and water in these situations:
- When hands are visibly dirty or visibly soiled with blood or body fluids
- After using the restroom
- When caring for a patient with known or suspected Clostridioides difficile (C. diff) infection
- During outbreaks of norovirus or other spore-forming organisms
- After exposure to certain chemicals or antimicrobial agents
Alcohol-based sanitizers do not effectively kill C. diff spores or norovirus. The physical friction of washing with soap and water helps remove these pathogens from the skin.
For all other routine moments, alcohol-based hand rub with 60-95% alcohol concentration is the standard choice. It works faster than soap and water and is more accessible at the point of care.
How Long Should Hand Hygiene Take?
The duration matters as much as the timing. Rushing the process reduces effectiveness.
For alcohol-based hand rub, apply enough product to cover all hand surfaces. Rub your hands together until they are dry. This typically takes about 20-30 seconds. The product must evaporate completely for full antimicrobial effect.
For soap and water, wet your hands, apply soap, and scrub all surfaces for at least 20 seconds. Rinse thoroughly and dry with a disposable towel. Use the towel to turn off the faucet to avoid recontaminating your hands.
These durations are based on established infection control guidelines. Proper technique — covering all surfaces including fingertips, thumbs, and between fingers — matters just as much as the time spent.
Do Gloves Replace Hand Hygiene?
No. Gloves are an additional layer of protection, not a replacement for hand hygiene.
Hands must be cleaned before putting on gloves. This prevents germs on your hands from contaminating the gloves during donning. Hands must also be cleaned after removing gloves. Gloves can have tiny defects or become contaminated during removal. Your hands can pick up germs from the glove surface.
Change gloves between tasks on the same patient when moving from a contaminated body site to a clean one. Change gloves between patients. Never wash or reuse disposable gloves.
Glove use does not change the five moments. You still clean your hands at each of those moments even when wearing gloves.
What Does the Evidence Say About Hand Hygiene Compliance?
Studies consistently show that healthcare worker hand hygiene compliance is lower than it should be. Observed compliance rates in hospitals typically range from 40-60%, though this varies widely by setting and measurement method.
The reasons for non-compliance are well documented. Heavy workload, time pressure, skin irritation from frequent washing, and forgetfulness all contribute. Some healthcare workers underestimate their own missed opportunities.
Multimodal improvement programs have shown the best results. These programs combine education, reminders, feedback on performance, and easy access to hand hygiene products. When healthcare facilities implement these strategies consistently, compliance improves.
Patient outcomes improve when hand hygiene compliance increases. Research consistently links better hand hygiene practices with lower rates of healthcare-associated infections, including surgical site infections, bloodstream infections, and urinary tract infections.
What About Hand Hygiene Before Food Preparation or Eating?
Healthcare professionals also need to clean their hands before handling food, eating, or preparing beverages. This applies in hospital cafeterias, break rooms, and anywhere staff handle food.
This is not one of the WHO’s five clinical moments, but it is a standard food safety requirement. Healthcare workers may carry resistant bacteria from patients to food items if they do not wash up first.
Soap and water is preferred before eating. If only hand sanitizer is available, use it thoroughly — but washing with soap and water is the better choice when you have been in a healthcare environment.
How Does Skin Condition Affect Hand Hygiene?
Healthy skin is essential for effective hand hygiene. Damaged or irritated skin harbors more bacteria and is harder to clean effectively.
Healthcare workers who wash their hands dozens of times per day frequently develop dry, cracked skin. This condition is called irritant contact dermatitis. It is common and treatable.
Use lotions and moisturizers approved by your healthcare facility. These products are tested to ensure they do not interfere with glove integrity or antimicrobial products. Avoid petroleum-based lotions that can degrade latex gloves.
If you develop persistent skin irritation, speak with occupational health. They can recommend alternative products or treatment options. Never skip hand hygiene because your skin is irritated — find a solution instead.
Frequently Asked Questions
How often should a healthcare professional clean their hands?
Healthcare professionals should clean their hands at every one of the five WHO moments — before and after patient contact, before aseptic procedures, after body fluid exposure, and after touching patient surroundings. The actual number varies by role and patient load, but it typically ranges from dozens to over a hundred times per shift.
Is hand sanitizer as good as soap and water for healthcare workers?
Alcohol-based hand sanitizer is the preferred method for routine hand hygiene in healthcare settings, but soap and water is required when hands are visibly dirty, after using the restroom, and when caring for patients with C. diff or norovirus. Sanitizer does not kill all spore-forming organisms that cause these infections.
What happens if a healthcare worker skips hand hygiene?
Skipping hand hygiene increases the risk of transmitting germs between patients and healthcare workers, which can lead to healthcare-associated infections. These infections cause significant illness, longer hospital stays, and in severe cases, death.
Do healthcare workers need to wash hands after removing gloves?
Yes. Hands must be cleaned after removing gloves because gloves can have tiny defects or become contaminated during removal. Hand hygiene before putting on gloves and after taking them off is a standard requirement.

