Most cases of diarrhea get better on their own within a few days, and the main treatment is replacing the water and salts your body is losing. Oral rehydration solutions are the first-line option for most people. Loperamide (Imodium) can slow diarrhea in adults who have no fever and no blood in their stool. Bismuth subsalicylate (Pepto-Bismol) is another over-the-counter option. Antibiotics are rarely needed and should only be used when a doctor recommends them.
The right choice depends on what is causing the diarrhea, how severe it is, and who you are. A healthy 40-year-old with a mild stomach bug has different needs than a 70-year-old on a diuretic or a parent managing a sick toddler. This article explains what works, what does not, and when diarrhea stops being a self-care problem.
What Can You Take For Diarrhea?
Oral rehydration solution (ORS) is the most important thing to take. It replaces water and electrolytes — mainly sodium, potassium, and chloride — that diarrhea strips from your body. You can buy ORS packets at most pharmacies or make a basic version at home using the World Health Organization recipe: 1 liter of clean water, 6 level teaspoons of sugar, and half a teaspoon of salt.
Beyond rehydration, the main over-the-counter options are:
- Loperamide (Imodium) — slows bowel movements by acting on opioid receptors in the gut. It does not treat the cause. Do not use it if you have a fever or bloody stools.
- Bismuth subsalicylate (Pepto-Bismol) — reduces fluid secretion in the gut. It can help with mild diarrhea and traveler’s diarrhea. It turns stools and tongue dark, which is harmless but surprising.
- Probiotics — some strains show modest benefit in certain types of diarrhea, but results vary widely by strain and cause.
- Zinc supplements — recommended by the World Health Organization for children with diarrhea in low-resource settings. Not standard for adults in the US.
Prescription antibiotics are reserved for specific situations: confirmed bacterial infections, severe traveler’s diarrhea, or diarrhea in people with weakened immune systems. Most diarrhea in the US is viral, and antibiotics do nothing for viruses.
What Is the Most Important Treatment for Diarrhea?
Rehydration. This is not a minor point. Dehydration is what makes diarrhea dangerous, especially in children and older adults. The diarrhea itself is uncomfortable. The fluid loss is what sends people to the hospital.
Water alone is not enough. When you lose fluids through diarrhea, you also lose sodium and potassium. Drinking plain water dilutes the remaining electrolytes in your body and can make things worse in severe cases. That is why ORS exists — it has the right balance of sugar and salt to help your gut absorb water efficiently.
Sip small amounts frequently rather than drinking large amounts at once. If you vomit, wait a few minutes and try again. A few teaspoons every few minutes adds up.
Signs of dehydration to watch for:
- Dark yellow urine or not urinating much
- Dry mouth and lips
- Feeling dizzy when standing up
- Fatigue or confusion
- In children: no tears when crying, sunken eyes, unusual sleepiness
If you see these signs, especially in a child or an older adult, contact a doctor. Severe dehydration may need intravenous fluids.
Should You Take Loperamide or Pepto-Bismol?
Both can reduce how often you go to the bathroom, but they work differently and are not right for every situation.
Loperamide slows the muscles in your intestines. It is effective for mild, watery diarrhea without fever or blood. It is not safe when you have a fever or bloody stools because slowing the gut can trap infectious bacteria or toxins inside, making the illness worse. Do not give loperamide to children under 2 years old. For children between 2 and 12, ask a doctor first.
Bismuth subsalicylate reduces inflammation and fluid secretion. It is often used for traveler’s diarrhea and mild upset stomach. It contains salicylate, which is related to aspirin. Do not use it if you are allergic to aspirin, if you have a bleeding disorder, or if you are giving it to a child or teenager recovering from a viral illness, because of the risk of Reye’s syndrome.
Neither medication treats the underlying cause. They manage symptoms. If diarrhea lasts more than two days in an adult or more than 24 hours in a child, stop self-treating and call a doctor.
Do Probiotics Help With Diarrhea?
Some probiotics help in specific situations. The evidence is strongest for antibiotic-associated diarrhea and some cases of infectious diarrhea. But not all probiotics are the same. Different strains have different effects, and many products on the market have not been tested in clinical trials.
Two strains that have been studied more than most are Saccharomyces boulardii and Lactobacillus rhamnosus GG. Some research suggests they may shorten diarrhea by about a day in certain cases. That is a modest benefit, not a cure.
Probiotics are generally considered safe for healthy adults. They are not recommended for people who are severely immunocompromised or who have central venous catheters, because of rare reports of infection from the probiotic organisms themselves.
If you want to try a probiotic, choose one with a specific strain listed on the label and a dose that matches what was used in studies. If the label does not say the strain, the product has not been formulated with evidence in mind.
When Should You See a Doctor for Diarrhea?
Most diarrhea resolves without medical care. But some signs mean you should not wait.
- Diarrhea lasting more than 2 days in an adult or more than 24 hours in a child
- Blood or mucus in your stool
- Fever above 102°F (38.9°C)
- Severe pain in your abdomen or rectum
- Signs of dehydration that do not improve with fluids
- Diarrhea after recent antibiotic use or hospitalization
- Diarrhea in someone with a weakened immune system
Also see a doctor if you have traveled recently to a region with poor sanitation, or if you have been diagnosed with a chronic condition like inflammatory bowel disease or irritable bowel syndrome, since diarrhea can signal a flare.
For infants, call a doctor at the first sign of diarrhea if they are under 6 months old or if they are not feeding well. Young infants can dehydrate quickly.
What Should You Eat and Drink While You Have Diarrhea?
You do not need to starve yourself. In fact, eating helps your gut recover. The old advice to avoid all food is outdated.
Focus on simple, easy-to-digest foods:
- Bananas, rice, applesauce, toast (the BRAT diet — helpful short-term but not complete nutrition)
- Plain crackers, oatmeal, boiled potatoes
- Cooked carrots, squash, or other soft vegetables
- Lean meats like chicken or turkey without heavy sauces
- Broth or soup with salt
Avoid foods that can make diarrhea worse:
- Dairy (except yogurt with live cultures, which some people tolerate)
- Fried, greasy, or very spicy foods
- High-fiber foods like raw vegetables, beans, and bran
- Alcohol and caffeine
- Sugar-free products with sorbitol, mannitol, or xylitol
Drink ORS throughout the day. If you cannot get ORS, alternate between water and a salty broth. Sports drinks are better than plain water but have more sugar and less sodium than proper ORS, so they are not a perfect substitute.
What About Antibiotics and Prescription Medications?
Antibiotics are not a routine treatment for diarrhea. They are used when a doctor identifies a specific bacterial cause, such as certain strains of E. coli, Salmonella, Shigella, or Campylobacter. Even then, many bacterial diarrheas clear on their own without antibiotics.
Using antibiotics when they are not needed carries real risks: side effects, disruption of your gut bacteria, and contributing to antibiotic resistance. Some infections, like those caused by certain E. coli strains, can actually get worse with antibiotics because the drugs cause the bacteria to release more toxin.
Prescription medications your doctor might consider include:
- Antibiotics — for confirmed or strongly suspected bacterial infections
- Antiparasitic drugs — for giardiasis or other parasitic infections
- Antiemetics — to control vomiting so you can keep fluids down
- IV fluids — for moderate to severe dehydration
If you have diarrhea after recent antibiotic use, tell your doctor. Clostridioides difficile infection is a serious condition that needs specific treatment and should not be managed with over-the-counter anti-diarrheal drugs.
What Does Not Work for Diarrhea?
Several popular remedies have little or no evidence behind them.
- Activated charcoal — marketed for stomach bugs, but no good evidence shows it helps with diarrhea. It can interfere with medication absorption.
- Apple cider vinegar — no clinical evidence supports it for diarrhea.
- Herbal “cleanses” or detox teas — many contain laxative ingredients that make diarrhea worse.
- Large doses of vitamin C — can cause diarrhea rather than treat it.
If a product promises to “stop diarrhea fast” without explaining how, be skeptical. The most effective treatments are unglamorous: fluids, electrolytes, and time.
Frequently Asked Questions
What is the best thing to take for diarrhea?
Oral rehydration solution is the most important treatment because it replaces lost water and electrolytes. Loperamide or bismuth subsalicylate can reduce symptoms in adults without fever or bloody stools.
Can I take Imodium if I have a fever?
No. Loperamide should not be used when you have a fever or bloody diarrhea because slowing the gut can trap infectious organisms and worsen the illness.
How long should diarrhea last before I see a doctor?
See a doctor if diarrhea lasts more than 2 days in an adult or more than 24 hours in a child. Also seek care sooner if you have signs of dehydration, high fever, or blood in your stool.
Do probiotics really help with diarrhea?
Some strains, like Saccharomyces boulardii and Lactobacillus rhamnosus GG, may shorten diarrhea by about a day in certain cases. Results vary by strain and cause, so they are not a guaranteed fix.

