Plan B One-Step is a single levonorgestrel 1.5 mg tablet taken as soon as possible after unprotected sex or contraceptive failure. It works best within 72 hours, and the sooner you take it, the more effective it is. It is not an abortion pill, and it will not end an existing pregnancy.
What Is Plan B and How Does It Actually Work?
Plan B is emergency contraception. The active ingredient is levonorgestrel, a synthetic form of progesterone used in many hormonal birth control methods.
The main way it works is by delaying ovulation. If the ovary has not yet released an egg, levonorgestrel can hold that release back long enough for sperm to die off naturally. Sperm generally survive in the reproductive tract for up to about five days. If ovulation can be delayed past that window, fertilization cannot happen.
This is the part many people get wrong. Plan B does not prevent a fertilized egg from implanting. It does not interrupt an established pregnancy. Research on levonorgestrel’s mechanism has largely ruled out post-fertilization effects as a meaningful pathway. The label and major medical organizations agree on this point.
What it also does not do is work after ovulation has already occurred. Once the egg is released, Plan B has no pathway to prevent pregnancy from that act. This is why timing matters so much, and why the drug is not equally effective across the whole 72-hour window.
How To Take Plan B Correctly: Timing And Effectiveness
Take one 1.5 mg tablet by mouth as soon as possible. That is the entire dose. There is no second pill to take later, and no need to repeat it.
Effectiveness drops as time passes. The clearest way to think about it is in three windows.
- Within 24 hours: This is when Plan B works best. Most pregnancies that would have occurred are prevented.
- 24 to 72 hours: Still effective, but less so than in the first day. The decline is real and steady.
- 72 to 120 hours: Some evidence supports use up to 120 hours, but effectiveness in this window is notably lower. For this later window, a copper IUD is the more effective option if it is available to you.
You can take Plan B at any point in your menstrual cycle. You do not need a prescription if you are 17 or older in most US states, though age rules vary by state and you should check your local pharmacy. It can be taken with or without food.
A common mistake is assuming Plan B works the same regardless of when in your cycle you take it. It does not. If you are already near ovulation, the drug has less room to work. This is not a failure on your part. It is how the medication functions.
Does Plan B Cause Side Effects?
Yes, and they are usually temporary. The most common ones are nausea, headache, fatigue, and changes to your next period.
Nausea is the most frequent complaint. If you vomit within about two hours of taking the tablet, the dose may not have been fully absorbed, and you should talk to a pharmacist or clinician about whether to take another dose. Do not guess on this. Ask.
Your next period may come earlier, later, or be heavier or lighter than usual. This is expected and does not mean the medication failed. However, if your period is more than a week late, take a pregnancy test. Plan B is not perfect, and a late period is the signal to check.
Some people report breast tenderness and spotting between doses and their next period. These usually resolve without treatment.
Does Plan B Work If You Are Already Ovulating?
No. This is the single most important limitation of the drug, and it is worth stating plainly.
Plan B works by delaying ovulation. If the egg has already been released, there is nothing for it to delay. The sperm and egg can still meet, and pregnancy can still occur. No dose adjustment fixes this. Taking a second tablet does not help.
This is why the copper IUD is considered the most effective form of emergency contraception. It works by preventing fertilization and, if fertilization has already happened, by preventing implantation. It remains effective after ovulation. It is not a drug, and it requires a clinician to place it, usually within five days of unprotected sex. If you are past the 72-hour mark or you believe you may have already ovulated, ask a clinician about this option.
What Plan B Is Not
Plan B is not the abortion pill. This confusion is common and worth clearing up.
Medication abortion uses different drugs, mifepristone and misoprostol, and works by ending an established pregnancy. Plan B does not do this. It cannot end a pregnancy that has already implanted. If you are already pregnant, Plan B will not harm the pregnancy, and it will not end it.
Plan B is also not a substitute for ongoing birth control. It does not protect against sexually transmitted infections. It is not designed for repeated use as a primary method, though it is not dangerous to use more than once. If you find yourself needing it often, that is a signal to talk with a clinician about a method that fits your life better.
One more clarification. Plan B is not the same as ella (ulipristal acetate), another prescription emergency contraceptive. Ella is effective across a longer window and may work somewhat better for people with higher body weight. They are different drugs with different rules. Do not assume they are interchangeable.
What Affects How Well Plan B Works?
Body weight appears to play a role. Some research suggests levonorgestrel emergency contraception may be less effective in people with higher body mass index, though the evidence is not entirely consistent and the exact threshold is debated. The copper IUD does not appear to have this limitation. If this is a concern for you, a clinician can help you weigh the options.
Other medications can also matter. Some drugs that induce liver enzymes, including certain seizure medications and some HIV treatments, may reduce levonorgestrel’s effectiveness. The herbal supplement St. John’s wort is another example. If you take any of these, tell your pharmacist or clinician.
What does not affect it: your age within the approved range, whether you have eaten, and the day of your cycle in terms of whether you can take it. You can take it any day.
How to Get Plan B and What to Do Next
Plan B is available over the counter at most pharmacies and many grocery stores in the US. In most states, you do not need to show ID or be a certain age to buy it, though a few states have different rules. You can also order it online from reputable sellers.
After taking it, the main thing to watch is your next period. If it is more than a week late, take a pregnancy test. If you have severe lower abdominal pain, especially with a missed period, seek medical care promptly, because that combination can signal an ectopic pregnancy, which is a medical emergency.
Plan B is a backup, not a plan. It reduces the chance of pregnancy after one act of unprotected sex, but it does not eliminate it. If you want reliable ongoing protection, talk with a clinician about a method you can use consistently.
Frequently Asked Questions
How long after unprotected sex can I take Plan B?
Plan B is approved for use within 72 hours, and it works best the sooner you take it. Some evidence supports use up to 120 hours, but effectiveness in that later window is lower.
Can Plan B stop a pregnancy that has already started?
No. Plan B works mainly by delaying ovulation and cannot end an established pregnancy. If you are already pregnant, it will not terminate the pregnancy.
Does Plan B work if I have already ovulated?
No. Once the egg has been released, Plan B has no mechanism to prevent pregnancy from that act. A copper IUD is the more effective option in that situation.
What should I do if I vomit after taking Plan B?
If you vomit within about two hours of taking the tablet, the dose may not have been fully absorbed. Contact a pharmacist or clinician to find out whether you need another dose.

