You get hand, foot, and mouth disease (HFMD) by coming into close contact with a virus that spreads through saliva, nose and throat fluids, blister fluid, and stool. The most common cause is coxsackievirus A16, though other enteroviruses, including enterovirus 71, can also cause it. It is most contagious during the first week of illness, and the virus can stay in a child’s stool for weeks after symptoms clear.
Despite the name, it has nothing to do with animals’ hooves or feet. The name comes from the rash that appears on the hands, feet, and inside the mouth. It is a common childhood illness, usually mild, and most people recover on their own within a week to ten days.
How Do You Get Hand And Foot Disease?
HFMD spreads through person-to-person contact with infected body fluids. The virus enters through the mouth, nose, or eyes, or through breaks in the skin.
The main routes of transmission are:
- Respiratory droplets. Coughing, sneezing, or talking can send tiny droplets carrying the virus into the air, where another person breathes them in or they land on surfaces.
- Direct contact with blister fluid. Touching the fluid from an open blister and then touching your mouth or eyes can spread the virus.
- Fecal-oral contact. This is a major route, especially in young children who are not yet toilet trained. Changing a diaper and then touching your face without washing your hands can transmit the virus.
- Contaminated surfaces and objects. The virus can survive on toys, doorknobs, and other surfaces for a period of time. Sharing cups, utensils, or toys can pass it along.
The virus is present in saliva, nasal mucus, blister fluid, and stool. That is why close contact in households, daycare centers, and schools makes spread easy. A child can be contagious before the rash even appears, which makes containment difficult.
Who Is Most Likely to Get It?
HFMD affects children under age 5 most often, but anyone can get it. Adults and older children usually have some immunity from prior exposure, so they tend to get milder cases or none at all.
Outbreaks are common in childcare settings and schools. The illness occurs worldwide, and in temperate climates it tends to be more common in summer and early fall, though it can happen year-round.
Adults who do get it can sometimes have more uncomfortable symptoms than children, including a more painful sore throat and fatigue. Pregnant women and people with weakened immune systems should take extra care, since the virus can be more serious in these groups. Most healthy adults who catch it recover without complications.
What Are the Symptoms and How Long Do They Last?
Symptoms usually appear three to six days after exposure. The first signs are often a fever, sore throat, and a general feeling of being unwell.
A day or two later, painful sores can develop inside the mouth, on the tongue, and on the gums. A rash with flat spots or small blisters then appears on the palms of the hands and soles of the feet. The rash can also show up on the buttocks, knees, or elbows.
For most people, symptoms clear within seven to ten days. The mouth sores are often the most uncomfortable part, especially for young children who may refuse to eat or drink because it hurts to swallow. Watch for signs of dehydration, such as dry mouth, fewer wet diapers, or unusual sleepiness.
How Is It Treated?
There is no specific antiviral treatment for HFMD. Care focuses on relieving symptoms and preventing dehydration while the body clears the infection.
Over-the-counter pain and fever relievers such as acetaminophen or ibuprofen can ease discomfort. Do not give aspirin to children or teenagers because of the risk of Reye’s syndrome, a rare but serious condition.
For mouth pain, some clinicians suggest cold foods like popsicles or ice cream, or soft, bland foods that are easier to swallow. Avoid acidic or salty foods that can sting open sores. Offer fluids often in small amounts.
Most cases do not need medical care. Contact a doctor if a fever lasts more than a few days, if symptoms seem severe, if the person cannot keep fluids down, or if there are signs of dehydration. In rare cases, enterovirus 71 can cause complications involving the nervous system, so any severe symptoms such as stiff neck, confusion, or unusual weakness need prompt medical attention.
How Can You Prevent the Spread?
Handwashing is the most effective step. Wash hands with soap and water, especially after changing diapers, using the toilet, or handling a sick person, and before preparing food or eating.
Other practical steps include:
- Clean and disinfect frequently touched surfaces and toys.
- Do not share cups, utensils, or towels.
- Keep children with symptoms home from daycare or school while they have a fever and feel unwell.
- Cover coughs and sneezes with a tissue or elbow.
- Avoid close contact like kissing or hugging someone who is infected.
Children can usually return to school once the fever is gone and they feel well enough, even if some rash or peeling skin remains. The virus can linger in stool for weeks, so continued handwashing after toilet use matters long after the child seems better. There is no vaccine available in the United States for HFMD.
Is It the Same as Foot-and-Mouth Disease?
No. HFMD in humans is not the same as foot-and-mouth disease, which affects cattle, sheep, and pigs. The two are caused by completely different viruses.
Foot-and-mouth disease is an animal disease and does not infect humans. The similar names cause confusion, but there is no connection between them. A person cannot catch foot-and-mouth disease from animals, and animals do not catch HFMD from people.
When Should You See a Doctor?
Most cases resolve without medical care, but some situations warrant a call to a healthcare provider.
Seek medical advice if a fever lasts more than three days, if the person cannot drink enough fluids, if there are signs of dehydration, or if symptoms are unusually severe. For infants and young children, watch closely for refusal to feed and reduced urine output.
Any sign of neurological problems, such as a severe headache, stiff neck, confusion, or trouble walking, needs urgent evaluation. These are uncommon but should not be ignored.
Frequently Asked Questions
How long is hand, foot, and mouth disease contagious?
A person is most contagious during the first week of illness, when symptoms are present. The virus can remain in stool for several weeks after recovery, so handwashing should continue.
Can adults get hand, foot, and mouth disease?
Yes, adults can get it, though it is less common and usually milder due to prior exposure. Adults with weakened immune systems may have a more serious course.
Is hand, foot, and mouth disease the same as foot-and-mouth disease?
No, they are completely different diseases caused by unrelated viruses. Foot-and-mouth disease affects animals like cattle and pigs and does not infect humans.
Should a child with hand, foot, and mouth disease stay home from school?
Yes, keep a child home while they have a fever and feel unwell. They can usually return once the fever is gone and they feel well enough to participate.

